In order to explore an effective way to evaluate the comprehensive performance of high-quality development of China’s manufacturing industry based on low-carbon constraints, this paper, based on the analysis of research background, drew on the latest domestic and international research results and experience, and fully considered the actual situation of high-quality development of China's manufacturing industry based on low-carbon constraints. Among the five criteria-layer evaluation index of economic development, energy consumption, technological innovation, environmental pressure and environmental pollution governance, 30 representative operating-layer evaluation indicators were selected, and a fuzzy matter-element extension evaluation model for the comprehensive performance evaluation of China's provincial high-quality development based on low-carbon constraints was constructed. By using the relevant statistical data in China Statistical Yearbook, China Energy Statistical Yearbook and China Environmental Status Bulletin, this paper conducted an evaluation study on the comprehensive performance of high-quality development of China's manufacturing industry based on low-carbon constraints in 31 provinces, verified the effectiveness of the fuzzy matterelement extension evaluation model, and provided an effective quantitative analysis method for the comprehensive performance evaluation of high-quality development of China's manufacturing industry based on low-carbon constraints.