LETTERS TO EDITORS
Protective Influence of Natural Anthocyanins
of Aronia Melanocarpa on Selected Parameters
of Antioxidative Status in Experimental Intoxication
with Sulphide-2-Chloroethyl-3-Chloropropyl
E. Kowalczyk 1*, K. Charyk 1, P.Fijałkowski 1, J. Niedworok 1,
J.Błaszczyk 1, J. Kowalski 2
1 Department of Human Physiology and Biophysics,
2 Department of Internal Medicine and Cardiological Rehabilitation,
Medical University, Pl. Gen. J. Hallera 1, 90-647 Lódź, Poland
2 Department of Internal Medicine and Cardiological Rehabilitation,
Medical University, Pl. Gen. J. Hallera 1, 90-647 Lódź, Poland
Pol. J. Environ. Stud. 2004;13(3):339-341
KEYWORDS
ABSTRACT
Sulphide-2-chloroethyl-3-chloropropyl is an alkylating agent. It posssesses mutagenic and carcinogenic
properties, participates in oxidative processes and can induce lipid peroxidation.The aim of our
investigation was to define antioxidative activity of natural anthocyanins after single experimental intoxication
with sulphide-2-chloroethyl-3-chloropropyl in mice. Catalase activity in hemolysate, thiobarbituric
acid reacting substances (TBARS) concentration in hemolysate and selected organs were determined. The
study confirms increased lipid peroxidation as a result of sulphide-2-chloroethyl-3-chloropropyl intoxication,
but natural anthocyanines derived from Aronia Melanocarpa also seem to play a protective role as an
antioxidative agent.
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| eISSN: | 2083-5906 |
| ISSN: | 1230-1485 |
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