REVIEW PAPER
Phenols – Sources and Toxicity
J. Michałowicz, W. Duda
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University of Łódź, Faculty of Biology and Environment Protection,
Banacha 12/16 str., 90-237 Łódź, Poland
Pol. J. Environ. Stud. 2007;16(3):347-362
KEYWORDS
ABSTRACT
Phenols and their derivatives commonly exist in the environment. These compounds are used as the
components of dyes, polymers, drugs and other organic substances. The presence of phenols in the ecosystems
is also related with production and degradation of numerous pesticides and the generation of industrial
and municipal sewages. Some phenols are also formed during natural processes. These compounds may be
substituted with chlorine atoms, may be nitrated, methylated or alkylated. Both phenols and catechols are
harmful ecotoxins. Toxic action of these compounds stems from unspecified toxicity related to hydrophobocity
and also to the generation of organic radicals and reactive oxygen species. Phenols and catechols reveal
peroxidative capacity, they are hematotoxic and hepatotoxic, provoke mutagenesis and carcinogenesis
toward humans and other living organisms.