ORIGINAL RESEARCH
Hair Lead and Body Lead Burden in
Lead-Intoxicated Rats Fed Diets Enriched
with Dietary Fibre
Z. Krejpcio, J. Gawęcki
More details
Hide details
Department of Human Nutrition and Hygiene, August Cieszkowski Agricultural University,
Wojska Polskiego 31, 60-624 Pozna., Poland
Pol. J. Environ. Stud. 2002;11(2):123-126
KEYWORDS
ABSTRACT
In the factorial 23 design male Wistar rats were fed ad libitum diets supplemented with dietary fibre
preparations (fruit and maize preparations; 50 and 150 g/kg diet) and intoxicated with lead acetate per os
(200 and 400 mgPb/kg diet) for 5 weeks. At the end of the study, rats were anaesthetised and hair, liver,
kidney, spleen, and femoral bone were dissected for chemical analysis. It was found that: quantity of fibre in
the diet significantly affected inner organ and tissue lead contents in the rats. Dietary lead levels influenced
all analysed tissue and organ lead contents and the total body retention of lead in the rats. Positive correlations
were found between hair lead and inner organs lead (r = 0.35) and bone lead (r = 0.35), and total body
lead burden lead (r = 0.40).
This paper was presented in the 19th Workshop şMengen - und Spurenelementeş, Jena, Germany,
December 3-4, 1999.