Salinity is one of the main and common challenges in the world. This study was conducted to determine the effect of salinity and water requirements of peanuts, with main factors including water requirement 40% (WR₄), 60% (WR₃), 80% (WR₂), and 100% (WR₁); sub-treatment including salinity with values of 1 (S₁), 3 (S₂), 5 (S₃), and 7 (S₄) dS/m; and sub-sub-treatment including four cultivars Guil (V₁), Gorgani (V₂), Jonobi (V₃), and Mesri (V₄). The experimental design was conducted in the form of split factorial in a completely randomized block with 3 replications in 2015 and 2016. The results showed that the maximum seed yields in salinity levels of 1 dS m^-1 in 2015 and 2016 were 1,142 and 987 kg ha^-1, respectively. On the interaction effect of irrigation and salinity, maximum seed yields in 80% water requirement and salinity of 1 dS m^-1 in 2015 and 2016 were 1,393 and 1,265 kg ha^-1, respectively. The maximum seed yields in Jonobi cultivar with salinity of 1 dS m^-1 and in Guil cultivar in salinity of 5 dS m^-1 were 1,254 and 1,127 kg ha^-1, respectively. The Guil cultivar in 100% water requirement and with salinity of 1 dS m^-1 in 2015 and 2016 had the highest seed yield, with 1,883 and 1,710 kg ha^-1, respectively.