Synergistic development of eco-resilience, green technological innovation, and industrial digitization can help to increase resource efficiency, reduce environmental impacts, and facilitate industrial transformation, thereby contributing to the long-term sustainability of economic growth and social well-being. Using the super-efficient SBM model and the CRITIC-TOPSIS model, this paper measures the industrial digitalization efficiency, green technology innovation efficiency, and ecological resilience of 30 provinces in China from 2011-2021. It also analyzes the synergistic development, regional difference levels, and driving mechanisms of different regions using the coupled coordination degree, Dagum's Gini coefficient, and spatial econometric model. Results show that the overall level of synergistic development in most provinces is between mildly disordered and borderline disordered, and the quantitative relationship between different regions is shown as Northeast>West>Central>East. Meanwhile, the moderating effect of ecological resilience, green technology innovation, and industrial digitalization enhancement on the synergistic development of the three is more significant than the direct effect. Based on the econometric results, suggestions are made on the problems faced in the process of synergistic development of industrial digitalization, green technological innovation, and ecological resilience.