River erosion combined with the settling and sedimentation of deposits contributed to silting of the original meanders, cutting them off and forming two oxbow lakes. After the floods in 1997 and 2010 the valley of the meandering Odra River underwent further changes concerning water and sediment qualities. Since that time the quality of both water and sediments has been gradually improving, similar to that of surface waters. The analysis of water quality measurement results for the Odra at Chałupki showed that the values of water temperature, reaction, ammonia, and electrolytic conductivity do not exceed the limiting levels for class I. It appears that the Odra waters are not sensitive to pollution by nitrogen compounds from agricultural sources. The measurements of water sampled from the Odra show that indicators such as water temperature, dissolved oxygen, reaction, nitrites, and ammonia nitrogen meet the requirements for inland waters being the living environment for fish from the Salmonidae and the Cyprinidae families in natural conditions.